S Garavand; K Ebrahimi; M Zendehdel; K Keramati; M Amozad; E Noroze; F Gravand
Volume 2, Issue 4 , March 2014, , Pages 27-32
Abstract
Abstract Inthisstudytheeffectofhydroalcoholicextractofoliveleaf(Oleaeuropaea)onvisceralpainwasinvestigated. Forthispurpose,therehasbeenusedofmalemicewithweight(28±3g). Animalsweregroupedrandomlyintocontrol,positivecontrolandreceiversofoliveleafhydroalcoholicextract. Controlgroupandpositivecontrolgroupreceivednormalsaline0.9%andindomethacin(5mg/kg,i.p.),respectively. ...
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Abstract Inthisstudytheeffectofhydroalcoholicextractofoliveleaf(Oleaeuropaea)onvisceralpainwasinvestigated. Forthispurpose,therehasbeenusedofmalemicewithweight(28±3g). Animalsweregroupedrandomlyintocontrol,positivecontrolandreceiversofoliveleafhydroalcoholicextract. Controlgroupandpositivecontrolgroupreceivednormalsaline0.9%andindomethacin(5mg/kg,i.p.),respectively. Treatmentsgroupswereinjectedwithdoses,(125mg/kg,i.p.),(250mg/kg,i.p.)and(500mg/kg,i.p.)ofhydroalcoholicextractofoliveleaf. Animalswereinjectedwithaceticacid0.6%(10ml/kg)foriducingofvisceralpain,30minutesafterofeachintraperitonealadministration. andAnalgesiceffectwasrecordedbycountingthenumberofwrithes(elongations)immediatelyafterinjectionofaceticacidduring30minutes. Theresultsofthisstudywasshowedthathydroalcoholicextractofoliveleafwithuseddoseswitedosedependentmannerandindomethacin(5mg/kg,i.p.)inducedsignificantreductioninpainresponsecomparedtothecontrolgroup. P
